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\documentclass[a4paper,oneside]{memoir}
\usepackage[portrait,hmargin={2cm,2cm},vmargin={1cm,1cm}]{geometry}
\usepackage{lipsum}
\RequirePackage[draft]{flowfram}
\RequirePackage{color}
\RequirePackage{graphicx}
\usepackage{tikz}
\pagestyle{empty}
\renewcommand{\chapterfirstpagestyle}{empty}
\ffvadjustfalse
\onecolumninarea[1]{0.7\textwidth}{\textheight}{0pt}{0pt}
% if I changed onecolumninarea to twocolumninarea as following
% then no problem
% \twocolumninarea[1]{0.7\textwidth}{\textheight}{0pt}{0pt}
\twocolumninarea[>1]{\textwidth}{\textheight}{0pt}{0pt}
\newdynamicframe[1]{0.29\textwidth}{0.8\textheight}{0.71\textwidth}{0.1\textheight}[tocframe]
\setdynamiccontents*{tocframe}{\lipsum[1]}
\begin{document}
\includegraphics[scale=0.1]{uplogo}
\lipsum[1-10]
\chapter{Introduction}
\lipsum
\lipsum
\chapter{Introduction}
\lipsum
\lipsum
\end{document}