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Cross post here:
https://tex.stackexchange.com/questions ... lash-error

Please read the following:
https://latex.org/home/latex-community/ ... crossposts

Ah, that's because you have to have a layout file to be able to use the class in LyX. It can be difficult to learn how to make a layout file. If you want to go down that path, you can read Help > Customization. There is also some information on the web. see, e.g. https://wiki.lyx.org/Layouts/Layouts

Are those files found with kpsewhich?

Are you able to export the .lyx file to PDF with File > Export ?

Did this used to work for you or is this your first time using LyX?

Is it only for certain documents or even for a simple "hello world" document?

Hi and welcome to LyX and the forums!

Can you please post a minimal example? Please read the following:

https://wiki.lyx.org/FAQ/MinimalExample

After some troubleshooting, I made it wok finally. That's great news! In my Win10 system, "Ctrl+Space" is predefined already for switching between input methods, eg. English-Simplied Chinese. Therefore LyX conflicts with the system just for the Ctrl+space combination. Ah, good job figurin...

I do not have this issue, but I'm on Ubuntu. What keyboard layout do you use?

Did that shortcut work for you in the past?

When you insert it from the menu does it work?

I suggest starting with the template.

Go to File > New from Template and select the AGUTeX template. Does that compile for you?

Works for me with LyX version 2.3.0dev and with 2.2.x, on Ubuntu. I think this was fixed after 2.1.x. You might consider upgrading LyX when 2.3.1 is released (in a few months). That would be a good time. Make sure you always backup your documents before you upgrade and edit with newer versions of LyX.

I have no idea, but perhaps this is related to the following:

http://www.lyx.org/trac/ticket/10671

which will be fixed in the LyX 2.3.0rc2 (and 2.3.0 final) release.